Nanocomposites constructed by rare-earth fluoride and silver bismuth sulfide nanorods for efficient cancer therapy

Abstract

A novel photothermal therapy agent AgBiS2@PVP-NaYF4:Yb3+, Ho3+ multifunctional nanocomposite (NCs) was constructed. Through the research on the morphology, structure, and properties of the nanocomposite material, it was observed that the nanocomposites exhibited superior up-conversion luminescence (UCL) properties, remarkable photothermal conversion efficiency, and a highly effective photothermal cytotoxicity against tumor cells in vitro. Furthermore, the nanocomposites showed minimal cytotoxicity and excellent stability in MTT cell toxicity experiments. Consequently, the NCs represent a significant advancement for high-performance tumor photothermal therapy.